The combination of e–mail overload and interruptions is widely recognized as a major disrupter of knowledge worker productivity and quality of life, yet few organizations take serious action against it. This paper makes the case that this action should be a high priority, by analyzing the severe impact of the problem in both qualitative and quantitative terms. We attempt to provide sufficient supporting data from the scientific literature and from corporate surveys to enable change agents to make the case and convince their organizations to authorize such action.