Practitioners, however, have another purpose. They wish to know how to make their patients better. But until we can organize a compendium of mental illnesses according to a better working knowledge of the brain, the therapeutic revolution in psychiatry will have to wait. Neuroscientists and psychiatrists have certainly made prodigious strides -- and yet we are far from grasping how those swirling galaxies of neurons and molecules make us who we are, both in sickness and in mental health. Even as we gather light, we are still struggling in the dark.

From the archive:

A recent poll conducted by the Pew Research Center shows that almost 85 percent of Americans believe that they are very happy or at least pretty happy.

What drives this rage for complacency, this desperate contentment?

Are some people lying, or are they simply afraid to be honest in a culture in which the status quo is nothing short of manic bliss?

The Loss of Sadness: How Psychiatry Transformed Normal Sorrow Into Depressive Disorder