] One of the challenges of proteomics is sample size.
] Researchers need to fractionate complex protein mixtures
] into their component parts for subsequent analysis, but
] the miniscule quantities and volumes involved preclude
] standard large-scale chromatography. Three years ago
] Agilent Technologies, headquartered in Palo Alto, Calif.,
] introduced its 1100 series capillary LC system, featuring
] tiny tubes that could pump nanoliter volumes through
] columns with high accuracy. Now the company is following
] that up with a microfraction collection system for single
] or multidimensional separation of protein and peptide
] mixtures.

The Scientist :: Nano-LC for Proteomics, Jul. 14, 2003