Can burning excess fat be as easy as exhaling? That's the finding of a provocative new study by researchers at the University of California, Los Angeles (UCLA), who transplanted a fat-burning pathway used by bacteria and plants into mice. The genetic alterations enabled the animals to convert fat into carbon dioxide and remain lean while eating the equivalent of a fast-food diet.
The feat, detailed in the current issue of Cell Metabolism introduces a new approach to combating the growing obesity problem in humans. Although the proof-of-concept study is far from being tested in humans, it may point to new strategies for borrowing biological functions from bacteria and other species to improve human health.