"Strong earthquakes in the New Madrid seismic zone are certain to occur in the future," states a fact sheet from the U.S. Geological Survey. "There is a 9-in-10 chance of a magnitude 6 to 7 temblor occurring in the New Madrid Seismic Zone within the next 50 years."

I'd love to get the original article, but the $18 to Nature for it seems a bit steep.

New Data Confirms Strong Earthquake Risk to Central U.S.