An engineered material that can be injected into damaged spinal cords could help prevent scars and encourage damaged nerve fibers to grow. The liquid material, developed by Northwestern University materials science professor Samuel Stupp, contains molecules that self-assemble into nanofibers, which act as a scaffold on which nerve fibers grow.
Stupp and his colleagues described in a recent paper in the Journal of Neuroscience that treatment with the material restores function to the hind legs of paralyzed mice. Previously, researchers have restored function in the paralyzed hind legs of mice, but those experiments involved surgically implanting various types of material, while the new substance can simply be injected into the animals. The nanofibers break down into nutrients in three to eight weeks, says Stupp.
