] During replication, when the virus invades and colonises ] human cells, the RNA makes errors, resulting in genetic ] mutations to the prongs. Such mutations are known as ] 'antigenic drift'. The reason they are dangerous is that ] they trigger small changes to the haemagglutinin, ] enabling the prongs to stick better to human cells and ] evade the antibodies produced by the immune system. In ] addition, type A viruses such as H5N1 can also 'swap' or ] re-assort genetic material with other viruses. This ] process, known as 'antigenic shift', occurs when animal ] strains mix with human strains, producing viruses to ] which no animal or human has immunity. ] ] 'The problem is, one chicken can contain hundreds of ] thousands of strains of H5N1,' explains Oxford. A long, scary, interesting article about Bird Flu. The Observer | Magazine | On a wing and a prayer |