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This page contains all of the posts and discussion on MemeStreams referencing the following web page: On the death of Y chromosomes. You can find discussions on MemeStreams as you surf the web, even if you aren't a MemeStreams member, using the Threads Bookmarklet.
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On the death of Y chromosomes  by Decius at  8:28 am EDT, Sep 28, 2003 |  
] Of all our chromosomes, it is the only one that is ] permanently locked into the germ cells of men, where the ] frenzy of cell division and error-prone DNA copying ] required to keep up the daily output of 150 million sperm ] creates the ideal conditions for mutation. And it shows. ] Seven percent of men are infertile or sub-fertile and in ] roughly a quarter of cases the problem is traceable to ] new Y chromosome mutations, not present in their fathers, ] which disable one or other of the few remaining genes. ] This is an astonishingly high figure, and there is no ] reason to think things will improve in the future  --  ] quite the reverse in fact. One by one, Y chromosomes will ] disappear, eliminated by the relentless onslaught of ] irreparable mutation, until only one is left. When that ] chromosome finally succumbs, men will become extinct. ]  ] But when? I estimate that, at the current rate, male ] fertility caused by Y chromosome decay will decline to 1 ] percent of its present level within 5,000 generations  -- ]  roughly 125,000 years. Not exactly the day after ] tomorrow  --	but equally, not an unimaginably long time ] ahead. This is a very entertaining article, particularly if you are into genetic engineering. How well accepted is this theory?  |  
  
 
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RE: On the death of Y chromosomes  by k at  9:31 am EDT, Sep 28, 2003 |  
Decius wrote: ] ] Of all our chromosomes, it is the only one that is ] ] permanently locked into the germ cells of men, where the ] ] frenzy of cell division and error-prone DNA copying ] ] required to keep up the daily output of 150 million sperm ] ] creates the ideal conditions for mutation. And it shows. ] ] Seven percent of men are infertile or sub-fertile and in ] ] roughly a quarter of cases the problem is traceable to ] ] new Y chromosome mutations, not present in their fathers, ] ] which disable one or other of the few remaining genes. ] ] This is an astonishingly high figure, and there is no ] ] reason to think things will improve in the future  --  ] ] quite the reverse in fact. One by one, Y chromosomes will ] ] disappear, eliminated by the relentless onslaught of ] ] irreparable mutation, until only one is left. When that ] ] chromosome finally succumbs, men will become extinct. ] ]  ] ] But when? I estimate that, at the current rate, male ] ] fertility caused by Y chromosome decay will decline to 1 ] ] percent of its present level within 5,000 generations  -- ] ]  roughly 125,000 years. Not exactly the day after ] ] tomorrow  --  but equally, not an unimaginably long time ] ] ahead. ]  ] This is a very entertaining article, particularly if you are ] into genetic engineering. How well accepted is this theory? yeah, there's a chapter in Genome by Matt Ridley that discusses competition between the sex chromosomes, and how it's been whittling away the Y over generations.  i don't believe he makes the same conclusion, but it's an interesting read nonetheless.  |  
  
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