Holy sh!T!

Here, we show that these mutagenic tRNAs efficiently and specifically cause randomized proteome mutations and increasing levels of stress response activation depending on the mutation being introduced. As an example, we describe the utilization of this method for the identification of human microRNAs (miRNAs) that may be involved in the induction of apoptosis during late stages of the unfolded protein response.

From the ADAPT TO EVIL PURPOSES department