If you're tired of the pop-ups, blinking ad banners, interstitials, etc... but you still want the features of a general purpose portal site (custom news, weather, movie & tv listings, sports, stocks, etc...), this is the answer.

I used to use Excite, which is by the same people. This is the same portal engine, but without ads. They earn revenue through identified sponsored links on their Google-based search results.