Douglas Bowman:

Without conviction, doubt creeps in. Instincts fail. “Is this the right move?” When a company is filled with engineers, it turns to engineering to solve problems. Reduce each decision to a simple logic problem. Remove all subjectivity and just look at the data. Data in your favor? Ok, launch it. Data shows negative effects? Back to the drawing board. And that data eventually becomes a crutch for every decision, paralyzing the company and preventing it from making any daring design decisions.

Mark C. Taylor, on Jacques Derrida:

Belief not tempered by doubt poses a mortal danger.

Darth Vader:

I find your lack of faith disturbing.

Have you seen "Doubt"?

Father Brendan Flynn: You haven't the slightest proof of anything!
Sister Aloysius Beauvier: But I have my certainty!

Richard Hamming:

If you do not work on an important problem, it's unlikely you'll do important work.

Paul Graham:

It will always suck to work for large organizations, and the larger the organization, the more it will suck.