Computers are increasingly being introduced into safety-critical systems and, as a consequence, have been involved in accidents. Some of the most widely cited software-related accidents in safety-critical systems involved a computerized radiation therapy machine called the Therac-25. Between June 1985 and January 1987, six known accidents involved massive overdoses by the Therac-25 -- with resultant deaths and serious injuries. They have been described as the worst series of radiation accidents in the 35-year history of medical accelerators.
When good ideas go bad... really bad....