Paul Graham:

I'm not saying we should stop, but I think we should at least examine which lies we tell and why.

Bunk:

The bigger the lie, the more they believe.

From the Wikipedia summary:

Bunk makes this remark after perpetrating an elaborate hoax to trick a young suspect into confessing to a crime. Season 5 of the Wire will revolve around a series of lies, both public and private.

Paul Owen:

The big lie is a unifying theory ... We're led to a world in which a respected public servant has created an enormous lie, manufactured entirely bogus, disparate evidence, produced that evidence to an unquestioning media and prosecuted that lie at huge cost.

The big lie doesn't, of course, become a populist reality ... by repetition. To succeed it must be embraced and amplified by mainstream media.

Mark Bowden:

Journalism, done right, is enormously powerful precisely because it does not seek power. It seeks truth.

"Leonard Nimoy":

It's all lies. But they're entertaining lies. And in the end, isn't that the real truth?

The answer ... is No.